Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Cash Flows

v3.22.4
Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Operating Activities:      
Net loss $ (42,350) $ (33,152) $ (14,730)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization [note 5] 236 250 255
Stock-based compensation [note 11[c] and note 11[e]] 3,270 2,187 1,286
Shares issued as settlement with trade vendor 26 41  
Accrued interest on SVB convertible debt [note 9] 1,170    
Changes in operating assets and liabilities:      
Grant receivable [note 4] 48 (153)  
Prepaid expenses and other assets (931) (228) (452)
Accounts payable 819 509 (527)
Accrued liabilities other 55 (245) 280
Accrued clinical liabilities 376 899 66
Accrued compensation (263) 466 358
Lease obligation (5) (14) (10)
Net cash used in operating activities (37,549) (29,440) (13,474)
Financing Activities:      
Proceeds from exercise of warrants 24 338 3,231
Receipt of convertible debt from SVB [note 9]   14,929  
Financing costs relating to convertible debt with SVB [note 9] (20)    
Proceeds from ATM, net of issuance costs [note 11b] 1,330    
Proceeds from employee stock purchase plan [note 11e] 126    
Taxes paid related to net share settlement of equity awards (47)    
Net cash provided by financing activities 19,295 36,610 32,680
Investing Activities:      
Purchase of property and equipment     (17)
Net cash provided by (used in) investing activities     (17)
Effect of exchange rate changes on cash 3 (1)  
Net increase (decrease) in cash, cash equivalents and restricted cash (18,251) 7,169 19,189
Cash, cash equivalents and restricted cash at beginning of year 43,072 35,903 16,714
Cash, cash equivalents and restricted cash at end of year 24,821 43,072 35,903
LPC [Member] | Purchase Agreement      
Financing Activities:      
Financing costs relating to purchase agreement with Lincoln Park Capital     (14)
December 2019 Public Offering [Member]      
Financing Activities:      
Financing costs relating to purchase agreement with Lincoln Park Capital     (34)
April 2020 Private Placement [Member]      
Financing Activities:      
Proceeds from purchase agreement with Lincoln Park Capital, net of issuance costs     1,579
July 2020 Registered Direct Offering [Member]      
Financing Activities:      
Proceeds from purchase agreement with Lincoln Park Capital, net of issuance costs     5,307
May 2021 Public Offering [Member]      
Financing Activities:      
Proceeds from offering, net of issuance costs   $ 21,343  
August 2020 Public Offering [Member]      
Financing Activities:      
Proceeds from offering, net of issuance costs     6,822
December 2020 Public Offering [Member]      
Financing Activities:      
Proceeds from offering, net of issuance costs     $ 15,789
November 2022 Private Placement [Member]      
Financing Activities:      
Proceeds from purchase agreement with Lincoln Park Capital, net of issuance costs $ 17,882