Annual report pursuant to Section 13 and 15(d)

Common Stock - Stock Warrants - Additional Information (Detail)

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Common Stock - Stock Warrants - Additional Information (Detail) - USD ($)
 12 Months Ended
Jun. 30, 2019
May 30, 2019
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Class of Warrant or Right [Line Items]          
Proceeds from exercise of warrants     $ 338,000 $ 3,231,000 $ 4,199,000
Expected volatility     110.10% 108.78%  
Risk-free interest rate     0.66% 0.94%  
Expected term     6 years 6 years  
Common stock, shares issued     9,453,542 6,111,735  
New Warrant [Member]          
Class of Warrant or Right [Line Items]          
Fair value of warrants recognized into accumulated deficit $ (3,900,000)        
Stock price $ 84.6        
Expected volatility 97.16%        
Risk-free interest rate 2.06%        
Expected term 6 years        
Warrants Issued in December 2019 [Member]          
Class of Warrant or Right [Line Items]          
Warrants to purchase common stock     47,084 489,952  
Exercise price per unit of warrant     $ 6.6000 $ 6.60  
Proceeds from exercise of warrants     $ 300,000 $ 3,200,000  
Warrants Issued in April 2020 [Member]          
Class of Warrant or Right [Line Items]          
Warrants to purchase common stock     3,750    
Exercise price per unit of warrant     $ 7.32    
Proceeds from exercise of warrants     $ 27,450    
Institutional Investor [Member]          
Class of Warrant or Right [Line Items]          
Proceeds from exercise of warrants   $ 4,200,000      
Institutional Investor [Member] | October 2018 Financing [Member]          
Class of Warrant or Right [Line Items]          
Warrants to purchase common stock   13,515      
Exercise price per unit of warrant   $ 62.89      
Institutional Investor [Member] | June 2018 Financing [Member]          
Class of Warrant or Right [Line Items]          
Warrants to purchase common stock   41,875      
Exercise price per unit of warrant   $ 80.00      
Institutional Investor [Member] | New Warrant [Member]          
Class of Warrant or Right [Line Items]          
Warrants to purchase common stock   60,000      
Exercise price per unit of warrant   $ 90      
Warrants, exercise period   6 years