Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Cash Flows

v3.22.0.1
Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended 40 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2020
Operating Activities:        
Net loss $ (33,152) $ (14,730) $ (16,395)  
Adjustments to reconcile net loss to net cash used in operating activities:        
Depreciation 27 32 31  
Amortization [note 5] 223 223 223  
Stock-based compensation [note 12[c]] 2,187 1,286 1,201  
Shares issued as settlement with trade vendor 41      
Cumulative adjustment on adoption of lease standard     (3)  
Changes in operating assets and liabilities:        
Grant receivable [note 4] (153)      
Prepaid expenses and other assets (228) (452) 194  
Accounts payable 509 (527) 715  
Accrued liabilities other (245) 280 (328)  
Accrued clinical liabilities 899 66 (812)  
Accrued compensation 466 358 (52)  
Lease obligation (14) (10) 10  
Net cash used in operating activities (29,440) (13,474) (15,216)  
Financing Activities:        
Proceeds from exercise of warrants 338 3,231 4,199  
Receipt of convertible debt from SVB [note 10] 14,929      
Net cash provided by financing activities 36,610 32,680 17,325  
Investing Activities:        
Purchase of property and equipment   (17) (53)  
Purchase of investments     (25)  
Maturities of investments     5,114  
Net cash provided by (used in) investing activities   (17) 5,036  
Effect of exchange rate changes on cash (1)   4  
Net increase (decrease) in cash, cash equivalents and restricted cash 7,169 19,189 7,149  
Cash, cash equivalents and restricted cash at beginning of year 35,903 16,714 9,565  
Cash, cash equivalents and restricted cash at end of year 43,072 35,903 16,714 $ 35,903
LPC [Member]        
Financing Activities:        
Financing costs relating to purchase agreement with Lincoln Park Capital       $ (500)
LPC [Member] | Purchase Agreement [Member]        
Financing Activities:        
Proceeds from purchase agreement with Lincoln Park Capital, net of issuance costs     792  
Financing costs relating to purchase agreement with Lincoln Park Capital   (14)    
December 2019 Public Offering [Member]        
Financing Activities:        
Financing costs relating to purchase agreement with Lincoln Park Capital   (34)    
Proceeds from public offering, net of issuance costs     $ 12,334  
April 2020 Private Placement [Member]        
Financing Activities:        
Proceeds from purchase agreement with Lincoln Park Capital, net of issuance costs   1,579    
July 2020 Registered Direct Offering [Member]        
Financing Activities:        
Proceeds from purchase agreement with Lincoln Park Capital, net of issuance costs   5,307    
May 2021 Public Offering [Member]        
Financing Activities:        
Proceeds from offering, net of issuance costs $ 21,343      
August 2020 Public Offering [Member]        
Financing Activities:        
Proceeds from offering, net of issuance costs   6,822    
December 2020 Public Offering [Member]        
Financing Activities:        
Proceeds from offering, net of issuance costs   $ 15,789