Subsequent Events - Additional Information (Detail) |
1 Months Ended | 12 Months Ended | |
|---|---|---|---|
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Apr. 24, 2015
USD ($)
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Feb. 29, 2016
USD ($)
Employee
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Dec. 31, 2015
USD ($)
shares
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| Subsequent Event [Member] | |||
| Subsequent Event [Line Items] | |||
| Reduction in workforce | Employee | 11 | ||
| Percentage of workforce reduction | 27.00% | ||
| Cash expenditures on workforce reduction | $ 400,000 | ||
| Chief Executive Officer | |||
| Subsequent Event [Line Items] | |||
| Consulting services paid | $ 500,000 | ||
| Stock options granted to purchase | shares | 37,500 | ||
| Restricted stock units granted | shares | 18,750 | ||
| Accounts payable, related parties | $ 400,000 | ||
| Collaborative Arrangement [Member] | Ionis Pharmaceuticals Inc. [Member] | |||
| Subsequent Event [Line Items] | |||
| Lawsuit filing date | January 5, 2016 | ||
| Proceeds from advance reimbursement research and development, net amount | $ 23,200,000 | ||
| Collaborative Arrangement [Member] | Ionis Pharmaceuticals Inc. [Member] | Maximum [Member] | |||
| Subsequent Event [Line Items] | |||
| Damages arise due to termination of agreement | $ 10,000,000 |
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- Definition Consulting services paid to related party. No definition available.
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- Definition Restricted stock units shares granted to related party. No definition available.
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- Definition Stock options granted shares to related party. No definition available.
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- Definition Amount for accounts payable to related parties. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition The value (monetary amount) of the award the plaintiff seeks in the legal matter. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition States the date the complaint was formally filed in a court of law, in arbitration or mediation. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Cash received from collaborators during the current period. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition The number of positions eliminated during the period as a result of restructuring activities. No definition available.
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- Definition The number of positions eliminated during the period as a percentage of total positions eliminated during the period in connection with the restructuring plan(s). No definition available.
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- Definition Amount of expenses for special or contractual termination benefits provided to current employees involuntarily terminated under a benefit arrangement associated exit or disposal activities pursuant to an authorized plan. Excludes expenses related to one-time termination benefits, a discontinued operation or an asset retirement obligation. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event. No definition available.
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