Annual report pursuant to Section 13 and 15(d)

Quarterly Financial Information - Quarterly Financial Information (Detail)

v2.4.1.9
Quarterly Financial Information - Quarterly Financial Information (Detail) (USD $)
In Thousands, except Per Share data, unless otherwise specified
3 Months Ended 12 Months Ended
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Quarterly Financial Information Disclosure [Abstract]                      
Collaboration revenue $ 5,653ogxi_RevenuesFromCollaborativeAgreements $ 4,803ogxi_RevenuesFromCollaborativeAgreements $ 4,929ogxi_RevenuesFromCollaborativeAgreements $ 11,731ogxi_RevenuesFromCollaborativeAgreements $ 8,604ogxi_RevenuesFromCollaborativeAgreements $ 9,862ogxi_RevenuesFromCollaborativeAgreements $ 6,340ogxi_RevenuesFromCollaborativeAgreements $ 5,076ogxi_RevenuesFromCollaborativeAgreements $ 27,116ogxi_RevenuesFromCollaborativeAgreements $ 29,882ogxi_RevenuesFromCollaborativeAgreements $ 20,095ogxi_RevenuesFromCollaborativeAgreements
Research and development 9,852us-gaap_ResearchAndDevelopmentExpense 9,586us-gaap_ResearchAndDevelopmentExpense 9,883us-gaap_ResearchAndDevelopmentExpense 16,903us-gaap_ResearchAndDevelopmentExpense 13,195us-gaap_ResearchAndDevelopmentExpense 18,004us-gaap_ResearchAndDevelopmentExpense 13,263us-gaap_ResearchAndDevelopmentExpense 10,855us-gaap_ResearchAndDevelopmentExpense 46,224us-gaap_ResearchAndDevelopmentExpense 55,317us-gaap_ResearchAndDevelopmentExpense 39,948us-gaap_ResearchAndDevelopmentExpense
General and administrative 2,733us-gaap_GeneralAndAdministrativeExpense 2,459us-gaap_GeneralAndAdministrativeExpense 2,676us-gaap_GeneralAndAdministrativeExpense 2,757us-gaap_GeneralAndAdministrativeExpense 2,446us-gaap_GeneralAndAdministrativeExpense 2,473us-gaap_GeneralAndAdministrativeExpense 2,473us-gaap_GeneralAndAdministrativeExpense 2,500us-gaap_GeneralAndAdministrativeExpense 10,625us-gaap_GeneralAndAdministrativeExpense 9,892us-gaap_GeneralAndAdministrativeExpense 7,791us-gaap_GeneralAndAdministrativeExpense
Restructuring gain (267)us-gaap_RestructuringCosts               (3,517)us-gaap_RestructuringCosts   (1,657)us-gaap_RestructuringCosts
Total expenses 12,318us-gaap_CostsAndExpenses 12,045us-gaap_CostsAndExpenses 12,559us-gaap_CostsAndExpenses 19,660us-gaap_CostsAndExpenses 15,641us-gaap_CostsAndExpenses 20,477us-gaap_CostsAndExpenses 15,736us-gaap_CostsAndExpenses 13,355us-gaap_CostsAndExpenses 56,582us-gaap_CostsAndExpenses 65,209us-gaap_CostsAndExpenses 46,082us-gaap_CostsAndExpenses
Other income 983us-gaap_NonoperatingIncomeExpense 2,335us-gaap_NonoperatingIncomeExpense 615us-gaap_NonoperatingIncomeExpense (707)us-gaap_NonoperatingIncomeExpense 359us-gaap_NonoperatingIncomeExpense 561us-gaap_NonoperatingIncomeExpense 976us-gaap_NonoperatingIncomeExpense 1,582us-gaap_NonoperatingIncomeExpense 3,226us-gaap_NonoperatingIncomeExpense 3,478us-gaap_NonoperatingIncomeExpense 4,889us-gaap_NonoperatingIncomeExpense
Net loss $ (5,682)us-gaap_NetIncomeLoss $ (4,907)us-gaap_NetIncomeLoss $ (7,015)us-gaap_NetIncomeLoss $ (8,636)us-gaap_NetIncomeLoss $ (6,678)us-gaap_NetIncomeLoss $ (10,054)us-gaap_NetIncomeLoss $ (8,420)us-gaap_NetIncomeLoss $ (6,697)us-gaap_NetIncomeLoss $ (26,240)us-gaap_NetIncomeLoss $ (31,849)us-gaap_NetIncomeLoss $ (21,098)us-gaap_NetIncomeLoss
Basic and diluted net loss per share $ (0.26)us-gaap_EarningsPerShareBasicAndDiluted $ (0.23)us-gaap_EarningsPerShareBasicAndDiluted $ (0.47)us-gaap_EarningsPerShareBasicAndDiluted $ (0.59)us-gaap_EarningsPerShareBasicAndDiluted $ (0.45)us-gaap_EarningsPerShareBasicAndDiluted $ (0.68)us-gaap_EarningsPerShareBasicAndDiluted $ (0.57)us-gaap_EarningsPerShareBasicAndDiluted $ (0.46)us-gaap_EarningsPerShareBasicAndDiluted $ (1.45)us-gaap_EarningsPerShareBasicAndDiluted $ (2.17)us-gaap_EarningsPerShareBasicAndDiluted $ (1.56)us-gaap_EarningsPerShareBasicAndDiluted