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Accounting Policies (Details Textual) (USD $)
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12 Months Ended | |||
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Dec. 31, 2012
Segment
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Dec. 31, 2010
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Dec. 31, 2009
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Dec. 31, 2011
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| Accounting Policies (Textual) [Abstract] | ||||
| Maturity period of liquid investments | 3 months | |||
| Maturity period of financial instruments | Greater than three months and less than one year | |||
| Direct and indirect development costs | $ 30,000,000 | |||
| Revenue recognized on a proportional performance basis Under the collaboration agreement | 30,000,000 | |||
| Collaboration revenue | 0 | 18,271,000 | ||
| Revenue recognized | 22,000,000 | |||
| Achievement of developmental and commercial milestones | 370,000,000 | |||
| Royalties at percentage rates ranging | Mid-teens to mid-twenties on net sales | |||
| Laboratory capital assets exchanged for barter credit | 0 | |||
| Redemption period | 1 year | |||
| Pre-tax gain | $ 200,000 | |||
| Percentage of tax credits or grants | 50.00% | |||
| Number of Operating Segments | 1 | |||
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Restricted Stock [Member]
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| Accounting Policies [Line Items] | ||||
| Vested period | 4 years | |||
| X | ||||||||||
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- Details
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| X | ||||||||||
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- Details
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| X | ||||||||||
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- Definition
Amount to be recognized as revenue on proportional performance basis under agreement. No definition available.
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- Definition
Amount to be spent in direct and indirect development costs under agreement. No definition available.
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- Definition
Collaboration maximum additional payment received achievement of developmental and commercial milestones. No definition available.
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- Definition
Description of maturity period of financial instruments to be considered as short term investment. No definition available.
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- Definition
Laboratory capital asset exchanged for barter credit. No definition available.
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- Definition
Maturity period of highly liquid investments to be considered as cash equivalent. No definition available.
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- Definition
Maximum maturity period of short term investments. No definition available.
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- Definition
Royalties at percentage rates ranging. No definition available.
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- Definition
Tax credits or grants as percentage of eligible qualified investment. No definition available.
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| X | ||||||||||
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- Definition
The carrying amount of consideration received or receivable as of the balance sheet date on potential earnings that were not recognized as revenue in conformity with GAAP, and which are expected to be recognized as such within one year or the normal operating cycle, if longer, including sales, license fees, and royalties, but excluding interest income. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Revenue earned during the period relating to consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Disclosure of the difference in values (gain (loss)) between the nonmonetary assets or liabilities exchanged with another entity inclusive of boot (small monetary consideration). Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues. No definition available.
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| X | ||||||||||
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- Definition
Period which an employee's right to exercise an award is no longer contingent on satisfaction of either a service condition, market condition or a performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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