Annual report pursuant to Section 13 and 15(d)

Common Stock (Tables)

v2.4.0.6
Common Stock (Tables)
12 Months Ended
Dec. 31, 2012
Common Stock [Abstract]  
Summary of fair value option award
                         
    2012     2011     2010  

Risk-free interest rates

    0.96     1.70     2.73

Expected dividend yield

    0     0     0

Expected life

    5.9 years       5.9 years       6.8 years  

Expected volatility

    95     76     75
Summary of share-based compensation expense
                         
    Years ended
December 31,
 
    2012     2011     2010  
    $     $     $  

Research and development

    899       509       331  

General and administrative

    1,276       679       311  
   

 

 

   

 

 

   

 

 

 

Total stock-based compensation

    2,175       1,188       642  
Summary of stock options activity
                 
    Number of
Optioned
Common
Shares
    Weighted
Average
Exercise
Price
 
    #     $  

Balance, December 31, 2009

    802,871       6.95  

Option grants

    170,872       15.87  

Option cancellations

    (7,311     104.91  

Option exercises

    (194,956     4.22  

 

                 

Option forfeited

    (26,563     7.35  
   

 

 

   

 

 

 

Balance, December 31, 2010

    744,913       8.74  

Option grants

    101,600       15.72  

Option cancellations

    (22,986     13.95  

Option exercises

    (56,228     3.88  

Option forfeited

    (971     41.91  
   

 

 

   

 

 

 

Balance, December 31, 2011

    766,328       9.82  

Option grants

    172,650       12.97  

Option cancellations

    (12,309     9.10  

Option exercises

    (117,347     3.94  

Option forfeited

    (4,541     15.26  
   

 

 

   

 

 

 

Balance, December 31, 2012

    804,781       11.34  
Summary of stock options outstanding regarding the number of ordinary shares issuable upon exercise of outstanding options

Exercise Prices

  Number of Options     Weighted-
Average
Exercise  Price

$
    Weighted-
Average
Remaining
Contractual
Life

(in years)
 

$2.69 — $2.85

    34,000       2.69       2.82  

$2.86 — $3.56

    232,600       3.00       2.98  

$3.57 — $12.48

    68,840       10.12       6.85  

$12.49 — $12.81

    22,000       12.56       9.46  

$12.82 — $13.06

    118,750       13.00       9.35  

$13.07 — $15.74

    43,176       14.26       8.46  

$15.75 — $16.40

    121,700       15.97       7.95  

$16.41 — $17.67

    48,500       16.92       8.14  

$17.68 — $21.67

    39,115       18.95       5.24  

$21.68 — $22.28

    76,100       22.28       6.90  
   

 

 

   

 

 

   

 

 

 
       

Total

    804,781       11.34       6.26  
Summary of stock options outstanding regarding the number of ordinary shares issuable upon exercise of vested options

Exercise Prices

  Number of Options     Weighted-
Average
Exercise  Price

$
    Weighted-
Average
Remaining
Contractual
Life

(in years)
 

$2.69 — $2.85

    34,000       2.69       2.82  

$2.86 — $3.56

    232,600       3.00       2.98  

$3.57 — $12.48

    37,839       8.56       5.10  

$12.49 — $12.81

    42       12.61       9.91  

$12.82 — $13.06

    27,214       13.00       9.35  

$13.23 — $15.74

    20,111       14.48       7.75  

$15.75 — $16.40

    60,850       15.97       7.95  

$16.41 — $17.67

    21,906       16.91       8.12  

$17.68 — $21.67

    38,327       18.90       5.26  

$21.68 — $22.28

    57,076       22.28       6.90  
   

 

 

   

 

 

   

 

 

 
       

Total

    529,965       9.62       5.00  
Summary of restricted stock award activity
                                 
    2012     2011  
    Stock
Awards

#
    Weighted-
Average
Grant
Date

Fair
Value

$
    Stock
Awards

#
    Weighted-
Average

Grant
Date
Fair
Value

$
 

Outstanding January 1

                               

Granted

    180,085       13.01       —         —    

Vested

    —         —         —         —    

Forfeited and expired

    (8,000     13.00       —         —    
   

 

 

   

 

 

   

 

 

   

 

 

 

Outstanding December 31

    172,085       13.01       —         —    
Summary of fair value of warrants issued
                         
    Years ended December 31,  
    2012     2011     2010  

Risk-free interest rates

    0.34     0.55     2.01

Expected dividend yield

    0     0     0

Expected life

    2.8 years       3.8 years       4.8 years  

Expected volatility

    45     76     75
Computation of basic and diluted net loss attributable to common shareholders per share
                         
    Years ended December 31,  

(in thousands except shares and per share amounts)

  2012     2011     2010  
       

Numerator

                       
       

Net loss attributable to common shareholders

  $ 21,099     $ 14,673     $ 12,584  
       

Denominator

                       
       

Weighted average number of common shares outstanding

    13,522,723       9,729,340       7,030,903  
       

Basic and diluted net loss per common share

  $ 1.56     $ 1.51     $ 1.79