Annual report pursuant to Section 13 and 15(d)

Common Stock (Tables)

v3.6.0.2
Common Stock (Tables)
12 Months Ended
Dec. 31, 2016
Equity [Abstract]  
Schedule of Common Stock

Gross proceeds of $24.0 million and underwriting discounts and commissions and offering expenses of $1.6 million were allocated as follows:

 

 

 

 

 

 

 

Series B

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Pre-funded

 

 

Series A

 

 

Series B

 

 

 

 

 

 

 

Common

 

 

Common

 

 

Common

 

 

 

Common

 

 

Stock

 

 

Stock

 

 

Stock

 

 

 

Stock

 

 

Warrants

 

 

Warrants

 

 

Warrants

 

Units Issued

 

 

5,559,866

 

 

 

1,340,538

 

 

 

2,779,933

 

 

 

670,269

 

Gross Proceeds (in thousands)

 

$

14,084

 

 

$

3,387

 

 

$

5,261

 

 

$

1,268

 

Underwriting discount and offering expense (in thousands)

 

$

885

 

 

$

213

 

 

$

428

 

 

$

103

 

 

Summary of Fair Value of Option Awards

The estimated fair value of stock options granted in the respective periods was determined using the Black-Scholes option pricing model using the following weighted average assumptions:

 

 

 

2016

 

 

2015

 

 

2014

 

Risk-free interest rates

 

 

1.51

%

 

 

1.76

%

 

 

1.83

%

Expected dividend yield

 

 

0

%

 

 

0

%

 

 

0

%

Expected life

 

5.3 years

 

 

5.8 years

 

 

5.9 years

 

Expected volatility

 

 

72

%

 

 

63

%

 

 

82

%

 

Summary of Share-Based Compensation Expense

The results for the periods set forth below included stock-based compensation expense in the following expense categories of the consolidated statements of loss (in thousands):

 

 

 

Years ended

 

 

 

December 31,

 

 

 

2016

 

 

2015

 

 

2014

 

Research and development

 

$

803

 

 

$

1,111

 

 

$

1,893

 

General and administrative

 

 

846

 

 

 

1,217

 

 

 

1,967

 

Total stock-based compensation

 

$

1,649

 

 

$

2,328

 

 

$

3,860

 

 

Summary of Stock Options Activity

Stock option transactions and the number of stock options outstanding are summarized below:

 

 

 

Number of

 

 

Weighted

 

 

 

Optioned

 

 

Average

 

 

 

Common

 

 

Exercise

 

 

 

Shares

 

 

Price

 

Balance, January 1, 2014

 

 

1,007,491

 

 

$

11.39

 

Granted

 

 

382,097

 

 

 

8.97

 

Expired

 

 

(12,169

)

 

 

18.93

 

Exercised

 

 

(10,000

)

 

 

3.00

 

Forfeited

 

 

(84,000

)

 

 

12.14

 

Balance, December 31, 2014

 

 

1,283,419

 

 

$

10.55

 

Granted

 

 

502,047

 

 

 

1.91

 

Expired

 

 

(247,766

)

 

 

2.96

 

Exercised

 

 

(5,359

)

 

 

2.69

 

Forfeited

 

 

(53,120

)

 

 

14.37

 

Balance, December 31, 2015

 

 

1,479,221

 

 

$

8.78

 

Granted

 

 

1,635,250

 

 

 

0.86

 

Expired

 

 

(994,059

)

 

 

1.00

 

Exercised

 

 

 

 

 

 

Forfeited

 

 

(741,607

)

 

 

1.96

 

Balance, December 31, 2016

 

 

1,378,805

 

 

$

8.62

 

 

Summary of Stock Options Outstanding Regarding Number of Common Shares Issuable upon Exercise of Outstanding Options

(1) Number of common shares issuable upon exercise of outstanding options:

 

 

 

 

 

 

 

 

 

 

 

Weighted-

 

 

 

 

 

 

 

 

 

 

 

Average

 

 

 

 

 

 

 

 

 

 

 

Remaining

 

 

 

 

 

 

 

Weighted-

 

 

Contractual

 

 

 

 

 

 

 

Average

 

 

Life

 

Exercise Prices

 

Number of Options

 

 

Exercise Price

 

 

(in years)

 

$1.00 - $1.54

 

 

122,010

 

 

$

1.00

 

 

 

9.36

 

$1.55 - $1.88

 

 

337,298

 

 

 

1.86

 

 

 

7.96

 

$1.89 - $3.40

 

 

118,874

 

 

 

2.62

 

 

 

6.98

 

$3.41 - $11.70

 

 

78,447

 

 

 

7.70

 

 

 

5.72

 

$11.71 - $11.86

 

 

185,105

 

 

 

11.79

 

 

 

6.66

 

$11.87 - $11.99

 

 

144,699

 

 

 

11.95

 

 

 

5.64

 

$12.00- $13.08

 

 

132,650

 

 

 

12.88

 

 

 

4.97

 

$13.09 - $16.40

 

 

135,576

 

 

 

15.64

 

 

 

3.54

 

$16.41 - $21.67

 

 

63,446

 

 

 

17.74

 

 

 

3.56

 

$21.68 - $22.28

 

 

60,700

 

 

 

22.28

 

 

 

2.67

 

 

 

 

1,378,805

 

 

$

8.62

 

 

 

6.30

 

 

Summary of Stock Options Outstanding Regarding Number of Common Shares Issuable upon Exercise of Vested Options

(2) Number common shares issuable upon exercise of vested options:

 

 

 

 

 

 

 

 

 

 

 

Weighted-

 

 

 

 

 

 

 

 

 

 

 

Average

 

 

 

 

 

 

 

 

 

 

 

Remaining

 

 

 

 

 

 

 

Weighted-

 

 

Contractual

 

 

 

 

 

 

 

Average

 

 

Life

 

Exercise Prices

 

Number of Options

 

 

Exercise Price

 

 

(in years)

 

$1.00 - $1.54

 

 

510

 

 

$

1.21

 

 

 

0.42

 

$1.55 - $1.88

 

 

184,008

 

 

 

1.86

 

 

 

7.74

 

$1.89 - $3.40

 

 

90,275

 

 

 

2.51

 

 

 

6.76

 

$3.41 - $11.70

 

 

75,217

 

 

 

7.69

 

 

 

5.78

 

$11.71 - $11.86

 

 

140,269

 

 

 

11.79

 

 

 

6.58

 

$11.87 - $11.99

 

 

141,951

 

 

 

11.95

 

 

 

5.64

 

$12.00- $13.08

 

 

132,650

 

 

 

12.88

 

 

 

4.97

 

$13.09 - $16.40

 

 

135,503

 

 

 

15.64

 

 

 

3.54

 

$16.41 - $21.67

 

 

63,446

 

 

 

17.74

 

 

 

3.56

 

$21.68 - $22.28

 

 

60,700

 

 

 

22.28

 

 

 

2.67

 

 

 

 

1,024,529

 

 

$

10.54

 

 

 

5.58

 

 

Summary of Restricted Stock Unit Award Activity

The following table summarizes our restricted stock unit award activity during the years ended December 31, 2016, 2015 and 2014:

 

 

 

 

 

 

 

Weighted

 

 

 

Number

 

 

Average

 

 

 

of

 

 

Grant Date

 

 

 

Shares

 

 

Fair Value

 

Balance, January 1, 2014

 

 

356,589

 

 

$

12.06

 

Granted

 

 

814,800

 

 

 

6.48

 

Vested

 

 

(199,887

)

 

 

7.00

 

Forfeited or expired

 

 

(291,301

)

 

 

10.93

 

Balance, December 31, 2014

 

 

680,201

 

 

$

7.34

 

Granted

 

 

249,775

 

 

 

1.92

 

Vested

 

 

(269,401

)

 

 

8.08

 

Forfeited or expired

 

 

(19,816

)

 

 

7.27

 

Balance, December 31, 2015

 

 

640,759

 

 

$

4.92

 

Granted

 

 

 

 

 

 

Vested

 

 

(217,296

)

 

 

5.23

 

Forfeited or expired

 

 

(170,242

)

 

 

5.07

 

Balance, December 31, 2016

 

 

253,221

 

 

$

4.56

 

 

Summary of Outstanding Warrants

The following is a summary of outstanding warrants to purchase common stock at December 31, 2016:

 

 

 

Total

 

 

 

 

 

 

 

 

 

Outstanding

 

 

Exercise

 

 

 

 

 

and

 

 

price per

 

 

 

 

 

Exercisable

 

 

Share

 

 

Expiration Date

(1) Series A Warrants issued in July 2014 financing

 

 

2,779,933

 

 

 

4.00

 

 

July 2019

(2) Series B Warrants issued in July 2014 financing

 

 

670,269

 

 

 

4.00

 

 

July 2019

(3) Series A-1 Warrants issued in April 2015 financing

 

 

239,234

 

 

 

2.40

 

 

October 2020

 

Summary of Fair Value of Warrants Issued

The estimated fair value of warrants issued and classified as liabilities is reassessed at each reporting date using the Black-Scholes option pricing model.

  

 

 

As of

 

 

 

December 31,

 

Series A and Series B Warrant Valuation Assumptions

 

2016

 

 

2015

 

Risk-free interest rates

 

 

1.33

%

 

 

1.42

%

Expected dividend yield

 

 

0

%

 

 

0

%

Expected life

 

2.50 years

 

 

3.50 years

 

Expected volatility

 

 

95

%

 

 

77

%

 

Computation of Basic and Diluted Net Loss Attributable to Common Shareholders Per Share

The following table presents the computation of basic and diluted net loss attributable to common stockholders per share (in thousands, except per share and share amounts):

 

 

 

Years ended December 31,

 

 

 

2016

 

 

2015

 

 

2014

 

Numerator

 

 

 

 

 

 

 

 

 

 

 

 

Net loss

 

$

(20,129

)

 

$

(16,801

)

 

$

(26,240

)

Denominator

 

 

 

 

 

 

 

 

 

 

 

 

Weighted average number of common shares outstanding

 

 

29,949,432

 

 

 

26,147,344

 

 

 

18,098,799

 

Basic and diluted net loss per common share

 

$

(0.67

)

 

$

(0.64

)

 

$

(1.45

)