Annual report pursuant to Section 13 and 15(d)

Quarterly Financial Information (Unaudited) - Quarterly Financial Information (Detail)

v3.22.0.1
Quarterly Financial Information (Unaudited) - Quarterly Financial Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2021
Sep. 30, 2021
Jun. 30, 2021
Mar. 31, 2021
Dec. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Quarterly Financial Information Disclosure [Abstract]                      
Research and development $ 4,506 $ 4,591 $ 9,227 $ 5,642 $ 2,347 $ 1,891 $ 1,103 $ 1,541 $ 23,966 $ 6,882 $ 9,674
General and administrative 2,609 2,102 2,075 2,342 2,374 1,863 1,815 1,816 9,128 7,868 6,854
Total operating expenses 7,115 6,693 11,302 7,984 4,721 3,754 2,918 3,357 33,094 14,750 16,528
Other income (expense) (36) 2 (9) (15) (3) (10) (4) 37 (58) 20 133
Net loss and comprehensive loss $ (7,151) $ (6,691) $ (11,311) $ (7,999) $ (4,724) $ (3,764) $ (2,922) $ (3,320) $ (33,152) $ (14,730) $ (16,395)
Basic and diluted net loss per common share $ (0.76) $ (0.71) $ (1.53) $ (1.30) $ (1.11) $ (1.14) $ (1.68) $ (2.15) $ (4.08) $ (5.42) $ (39.76)