Annual report pursuant to Section 13 and 15(d)

Common Stock - Summary of Outstanding Warrants (Detail)

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Common Stock - Summary of Outstanding Warrants (Detail) - $ / shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Warrants Issued In September 2017 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 411  
Exercise price per Share $ 699.2000  
Expiration Date 2023-03  
Warrants Issued in June 2018 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 114,100  
Exercise price per Share $ 80.0000  
Expiration Date 2023-06  
Warrants Issued in October 2018 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 31,215  
Exercise price per Share $ 62.8900  
Expiration Date 2023-10  
Warrants Issued in May 2019 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 60,000  
Exercise price per Share $ 90.0000  
Expiration Date 2025-05  
Warrants Issued in December 2019 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 612,967  
Exercise price per Share $ 6.6000 $ 6.60
Expiration Date 2024-12  
Warrants Issued in April 2020 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 182,461  
Exercise price per Share $ 7.2400  
Expiration Date 2025-04  
Warrants Issued in April 2020 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 24,375  
Exercise price per Share $ 7.3200  
Expiration Date 2025-04  
Warrants Issued in April 2020 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 25,270  
Exercise price per Share $ 7.5900  
Expiration Date 2025-04  
Pre-Funded Warrants Issued in August 2020 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 142,857  
Exercise price per Share $ 0.0010  
Warrants Issued in December 2020 [Member]    
Class of Warrant or Right [Line Items]    
Total Outstanding and Exercisable 50,000  
Exercise price per Share $ 8.7500  
Expiration Date 2025-12