Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Cash Flows

v3.20.4
Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended 40 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2020
Operating Activities:        
Net loss $ (14,730) $ (16,395) $ (12,687)  
Adjustments to reconcile net loss to net cash used in operating activities:        
Depreciation 32 31 60  
Amortization 223 223 222  
Stock-based compensation [note 10[c]] 1,286 1,201 854  
Cumulative adjustment on adoption of lease standard   (3)    
Changes in operating assets and liabilities:        
Prepaid expenses and other assets (452) 194 (341)  
Accounts payable (527) 715 (69)  
Accrued liabilities other 280 (328) 310  
Accrued clinical liabilities 66 (812) 322  
Accrued compensation 358 (52) 710  
Lease obligation (10) 10 (4)  
Net cash used in operating activities (13,474) (15,216) (10,623)  
Financing Activities:        
Proceeds from exercise of warrants 3,231 4,199 1,324  
Net cash provided by financing activities 32,680 17,325 19,757  
Investing Activities:        
Purchase of property and equipment (17) (53) (46)  
Proceeds on disposal of assets     10  
Purchase of investments   (25) (5,539)  
Maturities of investments   5,114 450  
Net cash provided by (used in) investing activities (17) 5,036 (5,125)  
Effect of exchange rate changes on cash   4    
Net increase (decrease) in cash, cash equivalents and restricted cash 19,189 7,149 4,009  
Cash, cash equivalents and restricted cash at beginning of year 16,714 9,565 5,556  
Cash, cash equivalents and restricted cash at end of year 35,903 16,714 9,565 $ 35,903
LPC [Member]        
Financing Activities:        
Financing costs relating to public offering and purchase agreement       $ (500)
LPC [Member] | Purchase Agreement [Member]        
Financing Activities:        
Proceeds from purchase agreement and registered direct offering, net of issuance costs   792 1,279  
Financing costs relating to public offering and purchase agreement (14)      
December 2019 Public Offering [Member]        
Financing Activities:        
Financing costs relating to public offering and purchase agreement (34)      
Proceeds from public offering, net of issuance costs   $ 12,334    
June 2018 Public Offering [Member]        
Financing Activities:        
Proceeds from public offering, net of issuance costs     12,194  
October 2018 Registered Direct Offering [Member]        
Financing Activities:        
Proceeds from purchase agreement and registered direct offering, net of issuance costs     $ 4,960  
April 2020 Private Placement [Member]        
Financing Activities:        
Proceeds from purchase agreement and registered direct offering, net of issuance costs 1,579      
July 2020 Registered Direct Offering [Member]        
Financing Activities:        
Proceeds from purchase agreement and registered direct offering, net of issuance costs 5,307      
August 2020 Public Offering [Member]        
Financing Activities:        
Proceeds from offering, net of issuance costs 6,822      
December 2020 Public Offering [Member]        
Financing Activities:        
Proceeds from offering, net of issuance costs $ 15,789