Annual report pursuant to Section 13 and 15(d)

Common Stock - Issued and Outstanding Shares - Additional Information (Detail)

v3.20.4
Common Stock - Issued and Outstanding Shares - Additional Information (Detail) - USD ($)
12 Months Ended 40 Months Ended
Dec. 07, 2020
Aug. 03, 2020
Jul. 02, 2020
Apr. 28, 2020
Mar. 12, 2020
Dec. 31, 2019
Dec. 17, 2019
Oct. 03, 2018
Jun. 19, 2018
Jun. 15, 2018
May 22, 2018
Sep. 14, 2017
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Common stock, par value           $ 0.001             $ 0.001 $ 0.001   $ 0.001
Exercise price per unit of warrant                 $ 80.00              
Common stock, shares issued           1,474,258             6,111,735 1,474,258   6,111,735
Preferred stock, par value                         $ 0.001     $ 0.001
Warrant exercisable period                 5 years              
Cancellation of warrant description                         Additionally, subject to certain exceptions, if, after the June 19, 2018, (i) the volume weighted average price of our common stock for each of 30 consecutive trading days, or the 2018 Measurement Period, which 2018 Measurement Period commences on June 19, 2018, exceeds 300% of the exercise price (subject to adjustments for stock splits, recapitalizations, stock dividends and similar transactions), (ii) the average daily trading volume for such 2018 Measurement Period exceeds $500,000 per trading day and (iii) certain other equity conditions are met, and subject to a beneficial ownership limitation, then we may call for cancellation of all or any portion of the warrants then outstanding.      
Number of required consecutive days weighted average trading price for cancelation or recall of warrants                 30 days              
Minimum required trading price percentage over exercise price for cancelation or recall of warrants                 300.00%              
Minimum required trading volume value per day for cancelation or recall of warrants                 $ 500,000              
Gross proceeds from sale of warrants and units                         $ 13,800,000      
Warrant and units offering cost including underwriting discounts and commissions                         1,600,000      
Net proceeds from issuance of warrants and units                         12,200,000      
Proceeds from exercise of warrants                         $ 3,231,000 $ 4,199,000 $ 1,324,000  
Stock option exercises, Shares                         0 0    
Restricted stock unit settlements                         236 256    
Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Restricted stock unit settlements                         128 254 267  
July 2020 Registered Direct Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Gross proceeds from issuance of common stock     $ 6,000,000         $ 5,600,000                
Placement agent fees and offering expenses     700,000         600,000                
Proceeds from issuance of common stock     $ 5,300,000         $ 5,000,000                
July 2020 Registered Direct Offering [Member] | Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Common stock, shares issued     731,707         89,462         731,707   89,462  
Common stock, price per share     $ 8.20         $ 62.89                
April 2020 Private Placement [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Exercise price per unit of warrant               $ 62.89                
Common stock, shares issued       280,782                        
Warrant exercisable period               5 years                
Number of required consecutive days weighted average trading price for cancelation or recall of warrants                         30 days      
Maximum number of common shares issuable per warrant upon conversion               0.5                
Gross proceeds from issuance of common stock       $ 1,900,000                        
Warrants to purchase shares of common stock       0.75                        
Warrants to purchase shares of common stock, offering price per share       $ 6.60                        
Proceeds from exercise of warrants       $ 1,600,000                        
Percentage of exercise price exceeds in measurement period                         300.00%      
Average daily trading volume for measurement period                         $ 500,000      
April 2020 Private Placement [Member] | Placement Agent [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Exercise price per unit of warrant       $ 7.59                        
Number of common shares issuable conversion of warrants       25,270                        
April 2020 Private Placement [Member] | Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Common stock, shares issued                         280,782      
December 2019 Public Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Exercise price per unit of warrant             $ 6.60                  
Offering expenses                         $ 34,000      
Warrant exercisable period             5 years                  
Cancellation of warrant description                         Additionally, subject to certain exceptions, if, after December 17, 2019, (i) the volume weighted average price of the common stock for each of 30 consecutive trading days, or the 2019 Measurement Period, which 2019 Measurement Period commences on the closing date, exceeds 300% of the exercise price (subject to adjustments for stock splits, recapitalizations, stock dividends and similar transactions), (ii) the average daily trading volume for such 2019 Measurement Period exceeds $500,000 per trading day and (iii) certain other equity conditions are met, and subject to a beneficial ownership limitation, then we may call for cancellation of all or any portion of the warrants then outstanding.      
Number of required consecutive days weighted average trading price for cancelation or recall of warrants             30 days                  
Minimum required trading price percentage over exercise price for cancelation or recall of warrants             300.00%                  
Minimum required trading volume value per day for cancelation or recall of warrants             $ 500,000                  
Gross proceeds from sale of warrants and units                         $ 13,800,000      
Warrant and units offering cost including underwriting discounts and commissions                         1,500,000      
Net proceeds from issuance of warrants and units                         12,300,000      
Gross proceeds from issuance of common stock $ 17,300,000                              
Proceeds from issuance of common stock 15,800,000                              
Underwriting discounts and commissions and offering expenses $ 1,500,000                              
December 2019 Public Offering [Member] | Maximum [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Exercise price per unit of warrant             $ 1.2                  
December 2019 Public Offering [Member] | Representative's Warrant [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Number of common shares issuable conversion of warrants 50,000                              
Common stock, price per share $ 8.75                              
Adjustments to additional paid in capital $ 300,000                              
Warrant exercisable term 5 years                              
August 2020 Public Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Gross proceeds from issuance of common stock   $ 7,500,000                            
Proceeds from issuance of common stock   6,800,000                     $ 6,822,000      
Underwriting discounts and commissions and offering expenses   $ 700,000                            
August 2020 Public Offering [Member] | Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Common stock, shares issued   569,043                     569,043      
Common stock, price per share   $ 10.50                            
Underwriters Over-Allotment Option Exercise [Member] | Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Common stock, shares issued 322,500 92,856                            
December 2020 Public Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Proceeds from issuance of common stock                         $ 15,789,000      
December 2020 Public Offering [Member] | Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Common stock, shares issued 2,472,500                       2,472,500      
Common stock, price per share $ 7.00                              
Series A Convertible Preferred Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Preferred stock, par value           $ 0.001             $ 0.001 $ 0.001   $ 0.001
Preferred stock, shares converted           9,158                    
Preferred stock, shares outstanding           0             0 0   0
Series A Convertible Preferred Stock [Member] | Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Convertible preferred stock, shares issued upon conversion           114,475                    
Series B Convertible Preferred Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Preferred stock, par value           $ 0.001             $ 0.001 $ 0.001   $ 0.001
Preferred stock, shares outstanding           1,121             0 1,121   0
Series B Convertible Preferred Stock [Member] | December 2019 Public Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Preferred stock, shares converted                         6,256      
Preferred stock, shares outstanding                         0     0
Series B Convertible Preferred Stock [Member] | December 2019 Public Offering [Member] | Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Convertible preferred stock, shares issued upon conversion                         521,124      
Subscription Agreements Executed on April 27, 2020 [Member] | April 2020 Private Placement [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Exercise price per unit of warrant                         $ 7.24     $ 7.24
Subscription Agreements Executed on April 28, 2020 [Member] | April 2020 Private Placement [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Exercise price per unit of warrant                         $ 7.32     $ 7.32
Class A Units [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Issuance of new units in a public offering                 35,525              
Public offering, price per unit                 $ 80.00              
Description of stock units issued                         Each Class A Unit consisted of one share of our common stock and a warrant to purchase one share of common stock.      
Class A Units [Member] | December 2019 Public Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Issuance of new units in a public offering             478,875                  
Public offering, price per unit             $ 12.00                  
Description of stock units issued                         Each Class A Unit consisted of one share of our common stock and a warrant to purchase one share of common stock.      
Class B Units [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Issuance of new units in a public offering                 9,158              
Public offering, price per unit                 $ 1,000              
Description of stock units issued                         Each Class B Unit consisted of one share of Series A Convertible Preferred Stock, par value $0.001 per share, convertible at any time at the holder’s option into approximately 12 shares of common stock and warrants to purchase approximately 12 shares of common stock.      
Number of common shares issuable for each share of convertible preferred stock                 12              
Number of common shares issuable conversion of warrants                 12              
Class B Units [Member] | December 2019 Public Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Issuance of new units in a public offering             6,256                  
Public offering, price per unit             $ 999.60                  
Description of stock units issued                         Each Class B Unit consisted of one share of Series B Convertible Preferred Stock, par value $0.001 per share, convertible at any time at the holder’s option into 83 shares of common stock, and warrants to purchase 83 shares of common stock.      
Number of common shares issuable for each share of convertible preferred stock             83                  
Number of common shares issuable conversion of warrants             83                  
Class B Units [Member] | Series A Convertible Preferred Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Preferred stock, par value                 $ 0.001              
Class B Units [Member] | Series A Convertible Preferred Stock [Member] | December 2019 Public Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Preferred stock, par value             $ 0.001                  
Pre Funded Warrants | August 2020 Public Offering [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Number of common shares issuable conversion of warrants   142,857                            
Pre-funded warrant, offering price per share   $ 10.499                            
Pre Funded Warrants | August 2020 Public Offering [Member] | Common Stock [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Exercise price per unit of warrant   $ 0.001                            
Number of days of prior notice to achieve not in excess percentage of common stock shares owned by warrant holder   61 days                            
Pre Funded Warrants | August 2020 Public Offering [Member] | Common Stock [Member] | Maximum [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Percentage of shares of common stock owned by warrant holder   19.99%                            
Pre Funded Warrants | August 2020 Public Offering [Member] | Common Stock [Member] | Minimum [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Percentage of shares of common stock owned by warrant holder   9.99%                            
LPC [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Common stock value right to sell, maximum         $ 11,000,000                      
Common stock, par value         $ 0.001                      
Minimum percentage of common stock shares outstanding authorized to sell                     20.00%          
Initial purchase of common stock                               1,644
Common stock, shares issued                       617        
Payments related to expense reimbursement         $ 100,000                      
Common stock, shares issued                         0     27,868
Gross proceeds                               $ 4,400,000
Offering expenses                               $ 500,000
LPC [Member] | Purchase Agreement [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Common stock, purchase price                       $ 1.00        
Additional common stock value right to sell, maximum                       $ 10,000,000        
Additional purchase of common stock, maximum                       7,500        
Offering expenses                         $ 14,000      
LPC [Member] | Units [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Initial purchase of common stock                       1,644        
Common stock, purchase price                       $ 608        
Purchase agreement, description                         Unit consisting of (a) one share of our common stock and (b) one warrant to purchase one-quarter of a share of common stock at an exercise price of $699.20 per share, or Warrant. Each Warrant became exercisable six months following the issuance date until the date that is five years and six months after the issuance date and is subject to customary adjustments.      
Exercise price per unit of warrant                       $ 699.20        
Initial purchase of units consisting of common stock and warrants issued                       $ 1,000,000        
LPC [Member] | Other Units [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Number of warrants issued                       0        
Ladenburg Thalmann & Co. Inc [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Period granted for underwriting option             45 days     45 days            
Ladenburg Thalmann & Co. Inc [Member] | 2018 Overallotment Option [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Additional purchase of common stock and warrants, maximum                   22,500            
Overallotment option exercise date                   Jun. 18, 2018            
Ladenburg Thalmann & Co. Inc [Member] | 2019 Overallotment Option [Member]                                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                                
Additional purchase of common stock and warrants, maximum             150,000                  
Overallotment option exercise date             Dec. 17, 2019