Form: SCHEDULE 13G

Statement of Beneficial Ownership by Certain Investors

July 8, 2026






Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
Checkbox checked   Rule 13d-1(c)
Checkbox not checked   Rule 13d-1(d)




schemaVersion:


SCHEDULE 13G




Comment for Type of Reporting Person:  The reported share amount represents an aggregate of (i) 972,215 shares of common stock, par value $0.001 per share (the "Common Stock") of Achieve Life Sciences, Inc. (the "Issuer"), and (ii) 972,215 shares of Common Stock of the Issuer, which are issuable upon the exercise of certain warrants. The shares of Common Stock and warrants are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P. The percentage reported in row 11 herein is based on 105,410,089 shares of Common Stock of the Issuer outstanding, which is the sum of (i) 102,659,057 shares of Common Stock outstanding as of May 15, 2026, as reported by the Issuer in its proxy statement on Form DEF 14A, filed with the Securities and Exchange Commission (the "SEC") on June 8, 2026, and (ii) an aggregate of 2,751,032 shares of Common Stock issuable upon the exercise of warrants held by all the reporting persons. The warrants contain provisions that prevent these securities from being exercised into shares of Common Stock, if such exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities.


SCHEDULE 13G




Comment for Type of Reporting Person:  The reported share amount represents an aggregate of (i) 610,179 shares of Common Stock of the Issuer, and (ii) 610,179 shares of Common Stock of the Issuer, which are issuable upon the exercise of certain warrants. The shares of Common Stock and warrants are held of record by Vivo Opportunity Co-Invest, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Co-Invest, L.P. The percentage reported in row 11 herein is based on 105,410,089 shares of Common Stock of the Issuer outstanding, which is the sum of (i) 102,659,057 shares of Common Stock outstanding as of May 15, 2026, as reported by the Issuer in its proxy statement on Form DEF 14A, filed with the SEC on June 8, 2026, and (ii) an aggregate of 2,751,032 shares of Common Stock issuable upon the exercise of warrants held by all the reporting persons. The warrants contain provisions that prevent these securities from being exercised into shares of Common Stock, if such exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities.


SCHEDULE 13G




Comment for Type of Reporting Person:  The reported share amount represents an aggregate of (i) 1,070,426 shares of Common Stock of the Issuer, and (ii) 1,070,426 shares of Common Stock of the Issuer, which are issuable upon the exercise of certain warrants. The shares of Common Stock and warrants are held of record by Vivo Opportunity Co-Invest (Cycle 3), L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Co-Invest (Cycle 3), L.P. The percentage reported in row 11 herein is based on 105,410,089 shares of Common Stock of the Issuer outstanding, which is the sum of (i) 102,659,057 shares of Common Stock outstanding as of May 15, 2026, as reported by the Issuer in its proxy statement on Form DEF 14A, filed with the SEC on June 8, 2026, and (ii) an aggregate of 2,751,032 shares of Common Stock issuable upon the exercise of warrants held by all the reporting persons. The warrants contain provisions that prevent these securities from being exercised into shares of Common Stock, if such exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities.


SCHEDULE 13G




Comment for Type of Reporting Person:  The reported share amount represents an aggregate of (i) 2,652,820 shares of Common Stock of the Issuer held by Vivo Opportunity Fund Holdings, L.P., Vivo Opportunity Co-Invest, L.P. and Vivo Opportunity Co-Invest (Cycle 3), L.P., and (ii) 2,652,820 shares of Common Stock of the Issuer, which are issuable upon the exercise of certain warrants held by Vivo Opportunity Fund Holdings, L,P., Vivo Opportunity Co-Invest, L.P. and Vivo Opportunity Co-Invest (Cycle 3), L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P., Vivo Opportunity Co-Invest, L.P. and Vivo Opportunity Co-Invest (Cycle 3), L.P. The percentage reported in row 11 herein is based on 105,410,089 shares of Common Stock of the Issuer outstanding, which is the sum of (i) 102,659,057 shares of Common Stock outstanding as of May 15, 2026, as reported by the Issuer in its proxy statement on Form DEF 14A, filed with the SEC on June 8, 2026, and (ii) an aggregate of 2,751,032 shares of Common Stock issuable upon the exercise of warrants held by all the reporting persons. The warrants contain provisions that prevent these securities from being exercised into shares of Common Stock, if such exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities.


SCHEDULE 13G




Comment for Type of Reporting Person:  The reported share amount represents an aggregate of (i) 98,212 shares of Common Stock of the Issuer, and (ii) 98,212 shares of Common Stock of the Issuer, which are issuable upon the exercise of certain warrants. The shares of Common Stock and warrants are held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P. The percentage reported in row 11 herein is based on 105,410,089 shares of Common Stock of the Issuer outstanding, which is the sum of (i) 102,659,057 shares of Common Stock outstanding as of May 15, 2026, as reported by the Issuer in its proxy statement on Form DEF 14A, filed with the SEC on June 8, 2026, and (ii) an aggregate of 2,751,032 shares of Common Stock issuable upon the exercise of warrants held by all the reporting persons. The warrants contain provisions that prevent these securities from being exercised into shares of Common Stock, if such exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities.


SCHEDULE 13G




Comment for Type of Reporting Person:  The reported share amount represents an aggregate of (i) 98,212 shares of Common Stock of the Issuer, and (ii) 98,212 shares of Common Stock of the Issuer, which are issuable upon the exercise of certain warrants. The shares of Common Stock and warrants are held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P. The percentage reported in row 11 herein is based on 105,410,089 shares of Common Stock of the Issuer outstanding, which is the sum of (i) 102,659,057 shares of Common Stock outstanding as of May 15, 2026, as reported by the Issuer in its proxy statement on Form DEF 14A, filed with the SEC on June 8, 2026, and (ii) an aggregate of 2,751,032 shares of Common Stock issuable upon the exercise of warrants held by all the reporting persons. The warrants contain provisions that prevent these securities from being exercised into shares of Common Stock, if such exercise would result in the holder or its affiliates obtaining greater than 9.99% of the Issuer's voting securities.


SCHEDULE 13G



 
Vivo Opportunity Fund Holdings, L.P.
 
Signature:/s/ Kevin Dai
Name/Title:Kevin Dai/Managing Member of Vivo Opportunity, LLC, General Partner
Date:07/08/2026
 
Vivo Opportunity Co-Invest, L.P.
 
Signature:/s/ Kevin Dai
Name/Title:Kevin Dai/Managing Member of Vivo Opportunity, LLC, General Partner
Date:07/08/2026
 
Vivo Opportunity Co-Invest (Cycle 3), L.P.
 
Signature:/s/ Kevin Dai
Name/Title:Kevin Dai/Managing Member of Vivo Opportunity, LLC, General Partner
Date:07/08/2026
 
Vivo Opportunity, LLC
 
Signature:/s/ Kevin Dai
Name/Title:Kevin Dai/Managing Member
Date:07/08/2026
 
Vivo Opportunity Cayman Fund, L.P.
 
Signature:/s/ Kevin Dai
Name/Title:Kevin Dai/Managing Member of Vivo Opportunity Cayman, LLC, General Partner
Date:07/08/2026
 
Vivo Opportunity Cayman, LLC
 
Signature:/s/ Kevin Dai
Name/Title:Kevin Dai/Managing Member
Date:07/08/2026
Exhibit Information

Exhibit 99.1 Joint Filing Statement