Consent of Independent Registered Public Accounting Firm
We hereby consent to the incorporation by reference in this registration statement on Form S-3 of Achieve Life Sciences, Inc. of our report dated March 10, 2022 relating to the financial statements of Achieve Life Sciences, Inc., which appears in Achieve Life Sciences, Inc.s Annual Report on Form 10-K for the year ended December 31, 2021. We also consent to the reference to us under the heading Experts in such registration statement.
/s/ PricewaterhouseCoopers LLP
Chartered Professional Accountants
December 29, 2022