Exhibit 31.1

Certification Pursuant to Rule 13a-14(a) or Rule 15d-14(a) of the Securities Exchange Act of 1934

        I, Michael A. Martino, certify that:

1.

I have reviewed this Amendment No. 1 to the annual report on Form 10-K of Sonus Pharmaceuticals, Inc.;



2.

Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

        Date: April 29, 2008

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Exhibit 31.1