Form: EFFECT

Notice of Effectiveness

May 22, 2026

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Notice of Effectiveness

Effectiveness Date: May 21, 2026 4:00 P.M.
Form: S-3
CIK: 0000949858
Company Name: ACHIEVE LIFE SCIENCES, INC.
File Number: 333-295798